3D Scans

Academic Articles

 

The following is a chronological list of all of the articles we have been able to find about FOXP1. If you find an article that you think would be useful for us to share here, please contact us.

2021

September

Individuals with FOXP1 syndrome present with a complex neurobehavioral profile with high rates of ADHD, anxiety, repetitive behaviors, and sensory symptoms

M. Pilar Trelles, Tess Levy, Bonnie Lerman, Paige Siper, Reymundo Lozano, Danielle Halpern, Hannah Walker, Jessica Zweifach, Yitzchak Frank, Jennifer Foss-Feig, Alexander Kolevzon & Joseph Buxbaum

2021

May

Severe speech impairment is a distinguishing feature of FOXP1-related disorder

Ruth O Braden, David J Amori, Simon E Fisher, Cristina Mei,
Candace T Muers, Heather Mefford, DeepakGill, Siddharth Srivastava,
Lindsay C Swanson, Himanshu Goel, Ingrid E Scheffer, Angela T Morgan

2021

April

FOXP1 syndrome: a review of the literature and practice parameters for medical assessment and monitoring

Reymundo Lozano, Catherine Gbekie, Paige M. Siper, Shubhika Srivastava, Jeffrey M. Saland, Swathi Sethuram, Lara Tang, Elodie Drapeau, Yitzchak Frank, Joseph D. Buxbaum & Alexander Kolevzon

2021

March

A genome-wide association study identifies a gene network associated with paranoid schizophrenia and antipsychotics-induced tardive dyskinesia

Anastasia Levchenko 1, Alexander Kanapin 2, Anastasia Samsonova 2, Olga Yu Fedorenko 3, Elena G Kornetova 4, Timur Nurgaliev 5, Galina E Mazo 6, Arkadiy V Semke 7, Alexander O Kibitov 8, Nikolay A Bokhan 9, Raul R Gainetdinov 10, Svetlana A Ivanova 11

2021

February

Autism-linked gene FoxP1 selectively regulates the cultural transmission of learned vocalizations

F Garcia-Oscos 1, T M I Koch 1, H Pancholi 1, M Trusel 1, V Daliparthi 1, M Co 1, S E Park 1, F Ayhan 1, D H Alam 1, J E Holdway 1, G Konopka 1, T F Roberts 2

2021

February

Ensemble Switching of the DNA-Binding Domain of Human FOXP1

Narendar Kolimi, Exequiel Medina, Cesar Ramirez-Sarmiento, Hugo Sanabria, Jorge Babul

2021

January

FOXP1 negatively regulates intrinsic excitability in D2 striatal projection  neurons by promoting inwardly rectifying and leak potassium currents 

Nitin Khandelwal 1, Sheridan Cavalier 1, Volodymyr Rybalchenko 1, Ashwinikumar  Kulkarni 1, Ashley G Anderson 1, Genevieve Konopka 2, Jay R Gibson 3 

2021

January

FOXP1 Interacts with MyoD to Repress its Transcription and Myoblast  Conversion 

Woodring E Wright 1, Chuan Li 2, Chang-Xue Zheng 3, Haley O Tucker 3

2020

December

Coupling of autism genes to tissue-wide expression and dysfunction of  synapse, calcium signaling and transcriptional regulation 

Jamie Reilly, Louise Gallagher, Geraldine Leader, Sanbing Shen 

2020

December

Identification of FoxP circuits involved in locomotion and object fixation  in Drosophila 

Ottavia Palazzo 1, Mathias Rass 1, Björn Brembs 1 

2020

November

Dysfunction of the corticostriatal pathway in autism spectrum disorders Wei Li 1, Lucas Pozzo-Miller 1 

2020

October

Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic  Urinary Tract Malformations 

Dervla M Connaughton et al. 

2020

September

Peruvian Newborn Male with 3p13 Deletion Syndrome Encompassing  the FOXP1 Gene: Review of the Literature 

Hugo H. Abarca-Barriga 

2020

September

Intrinsically Disordered Regions of the DNA-Binding Domain of Human  FoxP1 Facilitate Domain Swapping 

ExequielMedina1PabloVillalobos1George L.Hamilton2ElizabethA.Komives3HugoSanabria2César A.Ramírez-Sarmiento45JorgeBabul1

2020

September

FOXP transcription factors in vertebrate brain development, function, and  disorders 

Marissa Co 1, Ashley G Anderson 2, Genevieve Konopka 2 

2020

March

Single-Cell Analysis of Foxp1-Driven Mechanisms Essential for Striatal  Development 

Ashley G Anderson 1, Ashwinikumar Kulkarni 1, Matthew Harper 1, Genevieve Konopka

2020

February

Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep  Layer Cortical Fates 

Caroline Alayne Pearson 1, Destaye M Moore 1, Haley O Tucker 2, Joseph D Dekker 2, Hui  Hu 3, Amaya Miquelajáuregui 4, Bennett G Novitch 5 

2020

January

FOXP transcription factors in vertebrate brain development, function, and  disorders 

Marissa Co Ashley G. Anderson Genevieve Konopka 

2019

December

Differential Song Deficits after Lentivirus-Mediated Knockdown of FoxP1,  FoxP2, or FoxP4 in Area X of Juvenile Zebra Finches 

Philipp Norton 1, Peggy Barschke 1, Constance Scharff 1, Ezequiel Mendoza 2

2019

October

Gastrointestinal dysfunction in autism displayed by altered motility and  achalasia in Foxp1 +/- mice 

Henning Fröhlich 1, Marie Luise Kollmeyer 1, Valerie Catherine Linz 1, Manuel  Stuhlinger 1, Dieter Groneberg 2, Amelie Reigl 2, Eugen Zizer 3, Andreas Friebe 2, Beate  Niesler 1 4, Gudrun Rappold 5 

2019

July

Identification of a de novo FOXP1 mutation and incidental discovery of  inherited genetic variants contributing to a case of autism spectrum  disorder and epilepsy 

Kristy Jay 1, Amit Mitra 2, Taylor Harding 1, David Matthes 3, Brian Van Ness 1

2019

July

An Autism-Related, Nonsense Foxp1 Mutant Induces Autophagy and Delays  Radial Migration of the Cortical Neurons 

Xue Li 1 2 3, Xin Han 1 2 3, Xiaomeng Tu 1 2 3, Dan Zhu 1 2 3, Yue Feng 1 2 3, Tian  Jiang 4, Youping Yang 4, Jia Qu 1 2 3, Jie-Guang Chen 1 2 3 

2019

March

Regulatory genes and pathways disrupted in autism spectrum disorders

Fatma Ayhan 1, Genevieve Konopka 2 

2019

February

Conserved regulation of neurodevelopmental processes and behavior by  FoxP in Drosophila 

Anna Castells-Nobau 1, Ilse Eidhof 1, Michaela Fenckova 1, Dova B Brenman Suttner 2, Jolanda M Scheffer-de Gooyert 1, Sheren Christine 1, Rosa L Schellevis 1, Kiran  van der Laan 1, Christine Quentin 3 4, Lisa van Ninhuijs 1, Falko Hofmann 1, Radoslaw  Ejsmont 5, Simon E Fisher 6 7, Jamie M Kramer 1, Stephan J Sigrist 3 4, Anne F  Simon 2, Annette Schenck 1 

2018

December

An Autism-Related, Nonsense Foxp1 Mutant Induces Autophagy and Delays  Radial Migration of the Cortical Neurons 

Urreizti, R., Damanti, S., Esteve, C. et al 

2018

November

Characterization of a recurrent missense mutation in the forkhead DNA binding domain of FOXP1 

Tyler B Johnson 1, Keegan Mechels 1, Ruthellen H Anderson 1, Jacob T Cain 1, David A  Sturdevant 1, Stephen Braddock 2, Hailey Pinz 2, Mark A Wilson 3, Megan Landsverk 4, Kyle  J Roux 5 6, Jill M Weimer 7 8 

2018

October

Whole genome sequencing identifies a de novo 2.1 Mb balanced paracentric  inversion disrupting FOXP1 and leading to severe intellectual disability 

M-L Vuillaume 1, B Cogné 2, M Jeanne 1, A Boland 3, D-C Ung 4, D Quinquis 5, T  Besnard 5, J-F Deleuze 3, R Redon 6, S Bézieau 2, F Laumonnier 1, A Toutain 7 

2018

September

Differential and Overlapping Pattern of Foxp1 and Foxp2 Expression in the  Striatum of Adult Mouse Brain 

Weng Lam Fong 1, Hsiao-Ying Kuo 1, Hsiao-Lin Wu 1, Shih-Yun Chen 1, Fu-Chin Liu 2

2018

March

FOXP1-related intellectual disability syndrome: a recognizable entity

Ilse Meerschaut , Daniel Rochefort, Nicole Revençu, Justine Pètre, Christina Corsello,Guy A Rouleau (2017)

2018

January

A De Novo FOXP1 Truncating Mutation in a Patient Originally Diagnosed as  C Syndrome 

Roser Urreizti 1, Sarah Damanti 2 3, Carla Esteve 4, Héctor Franco-Valls 4, Laura Castilla Vallmanya 4, Raul Tonda 5 6, Bru Cormand 4, Lluïsa Vilageliu 4, John M Opitz 7, Giovanni  Neri 8, Daniel Grinberg 4, Susana Balcells 4 

2017

December

FOXP1 haploinsufficiency: Phenotypes beyond behavior and intellectual  disability? 

Angela Myers 1, Christèle du Souich 2 3, Connie L Yang 4, Lior Borovik 5, Jill  Mwenifumbo 3, Rosemarie Rupps 2 3, Causes Study 3, Anna Lehman 2 3, Cornelius F  Boerkoel 1 2 3 

2017

November

FOXP1-related intellectual disability syndrome: a recognisable entity 

Ilse Meerschaut , Daniel Rochefort, Nicole Revençu, Justine Pètre, Christina Corsello,Guy  A Rouleau, 

2017

November

Foxp1 in Forebrain Pyramidal Neurons Controls Gene Expression Required  for Spatial Learning and Synaptic Plasticity 

Daniel J Araujo 1, Kazuya Toriumi 1 2, Christine O Escamilla 3, Ashwinikumar  Kulkarni 1, Ashley G Anderson 1, Matthew Harper 1, Noriyoshi Usui 1, Jacob  Ellegood 4, Jason P Lerch 4 5, Shari G Birnbaum 6, Haley O Tucker 7, Craig M  Powell 1 3 6, Genevieve Konopka 

2017

November

Equivalent missense variant in the FOXP2 and FOXP1 transcription factors  causes distinct neurodevelopmental disorders 

Elliot Sollis 1, Pelagia Deriziotis 1, Hirotomo Saitsu 2, Noriko Miyake 3, Naomichi  Matsumoto 3, Mariëtte J V Hoffer 4, Claudia A L Ruivenkamp 4, Mariëlle  Alders 5, Nobuhiko Okamoto 6, Emilia K Bijlsma 4, Astrid S Plomp 5, Simon E Fisher 1 7 

2017

November

FOXP1 Promotes Embryonic Neural Stem Cell Differentiation by  Repressing Jagged1 Expression 

Luca Braccioli 1, Stephin J Vervoort 2, Youri Adolfs 3, Cobi J Heijnen 4, Onur Basak 5, R  Jeroen Pasterkamp 3, Cora H Nijboer 6, Paul J Coffer 7 

2017

October

Foxp1 regulation of neonatal vocalizations via cortical development 

Noriyoshi Usui 1 2 3, Daniel J Araujo 1, Ashwinikumar Kulkarni 1, Marissa Co 1, Jacob  Ellegood 4, Matthew Harper 1, Kazuya Toriumi 1 5, Jason P Lerch 4 6, Genevieve Konopka 1 

2017

October

Prospective investigation of FOXP1 syndrome 

Paige M Siper # 1 2, Silvia De Rubeis # 1 2, Maria Del Pilar Trelles 1 2, Allison  Durkin 1 2, Daniele Di Marino 3, François Muratet 1 2, Yitzchak Frank 1 2, Reymundo  Lozano 4 2, Evan E Eichler 5, Morgan Kelly 6, Jennifer Beighley 6, Jennifer Gerdts 6, Arianne S  Wallace 6, Heather C Mefford 6, Raphael A Bernier 6, Alexander Kolevzon # 7 2, Joseph D  Buxbaum 

2017

April

Foxp1 expression is essential for sex-specific murine neonatal ultrasonic  vocalization 

Henning Fröhlich 1, Rafiullah Rafiullah 1, Nathalie Schmitt 1, Sonja Abele 1, Gudrun A  Rappold 1 2 

2017

April

SUMOylation of FOXP1 regulates transcriptional repression via CtBP1 to  drive dendritic morphogenesis 

Daniel L Rocca 1, Kevin A Wilkinson 1, Jeremy M Henley 

2016

August

FoxP1 marks medium spiny neurons from precursors to maturity and is  required for their differentiation 

S V Precious 1, C M Kelly 1, A E Reddington 1, N N Vinh 1, R C Stickland 1, V Pekarik 2, C  Scherf 3, R Jeyasingham 1, J Glasbey 1, M Holeiter 1, L Jones 4, M V Taylor 5, A E Rosser 6 

2016

July

The RNA binding protein HuR determines the differential translation of  autism-associated FoxP subfamily members in the developing neocortex 

T Popovitchenko 1, K Thompson 1, B Viljetic 1, X Jiao 2, D L Kontonyiannis 3, M Kiledjian 2, R  P Hart 2, M R Rasin 1 

2016

March

Expression of forkhead box transcription factorgenes Foxp1 and Foxp2 during jaw  development 

Jeffry M.CesarioaAsma A.AlmaidhanbJuheeJeonga 

2016

February

Identification and functional characterization of de novo FOXP1 variants  provides novel insights into the etiology of neurodevelopmental disorder 

Elliot Sollis 1, Sarah A Graham 1, Arianna Vino 1, Henning Froehlich 2, Maaike  Vreeburg 3, Danai Dimitropoulou 1, Christian Gilissen 4, Rolph Pfundt 4, Gudrun A  Rappold 5, Han G Brunner 6, Pelagia Deriziotis 7, Simon E Fisher 8 

2015

October

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum 

Daniel J Araujo 1, Ashley G Anderson 1, Stefano Berto 1, Wesley Runnels 1, Matthew  Harper 1, Simon Ammanuel 1, Michael A Rieger 2, Hung-Chung Huang 3, Kacey  Rajkovich 1, Kristofer W Loerwald 1, Joseph D Dekker 4, Haley O Tucker 4, Joseph D  Dougherty 2, Jay R Gibson 1, Genevieve Konopka 1 

2015

July

Differential FoxP2 and FoxP1 expression in a vocal learning nucleus of the  developing budgerigar 

Osceola Whitney 1, Tawni Voyles 1, Erina Hara 1, Qianqian Chen 2, Stephanie A  White 2 3, Timothy F Wright 1 

2015

May

Brain-specific Foxp1 deletion impairs neuronal development and causes  autistic-like behaviour  

C Bacon1,2, M Schneider3,7, C Le Magueresse2,4,5,7, H Froehlich1,2, C Sticht6, C Gluch3,  H Monyer2,4 and GA Rappold1,2  

2015

May

Foxp1 regulates cortical radial migration and neuronal morphogenesis in  developing cerebral cortex 

Xue Li 1, Jian Xiao 1, Henning Fröhlich 2, Xiaomeng Tu 1, Lianlian Li 1, Yue Xu 1, Huateng  Cao 1, Jia Qu 1, Gudrun A Rappold 2, Jie-Guang Chen 1 

2015

April

A de novo FOXP1 variant in a patient with autism, intellectual disability and  severe speech and language impairment 

Reymundo Lozano 1, Arianna Vino 2, Cristina Lozano 1, Simon E Fisher 2 3, Pelagia  Deriziotis 2 

2015

February

Genetic Changes Shaping the Human Brain 

lByoung-IlBae1DivyaJayaraman1Christopher A.Walsh1 

2014

July

Clinical phenotype of a patient with FOXP1 deletion 

(T. Blanco Sánchez, et al., 2014) Article in Spanish 

2013

December

FOXP1 mutations cause intellectual disability and a recognizable phenotype 

Anna K Le Fevre 1, Sharelle Taylor, Neva H Malek, Denise Horn, Christopher W  Carr, Omar A Abdul-Rahman, Sherindan O'Donnell, Trent Burgess, Marie Shaw, Jozef  Gecz, Nicole Bain, Kerry Fagan, Matthew F Hunter 

2013

October

Expression analysis of the speech-related genes FoxP1 and FoxP2 and their  relation to singing behavior in two songbird species. 

Chen Q, Heston JB, Burkett ZD, White SA. 

2013

July

Increased gene expression of FOXP1 in patients with autism spectrum  disorders 

Wei-Hsien Chien 1, Susan Shur-Fen Gau, Chun-Houh Chen, Wen-Che Tsai, Yu-Yu Wu, Po Hsu Chen, Chi-Yung Shang, Chia-Hsiang Chen 

2013

March

Genetic Abnormalities in FOXP1 Are Associated with Congenital Heart Defects

(Sheng-Wei Chang, et al., 2013) 

2013

March

3p14.1 de novo microdeletion involving the FOXP1 gene in an adult patient  with autism, severe speech delay and deficit of motor coordination 

Orazio Palumbo 1, Leonardo D'Agruma, Adelaide Franca Minenna, Pietro  Palumbo, Raffaella Stallone, Teresa Palladino, Leopoldo Zelante, Massimo Carella 

2012

December

3p14.1 de novo microdeletion involving the FOXP1 gene in an adult patient  with autism, severe speech delay and deficit of motor coordination  

Orazio Palumbo a, Leonardo D'Agruma a, Adelaide Franca Minenna b, Pietro Palumbo  a,c, Raffaella Stallone a, Teresa Palladino a, Leopoldo Zelante a, Massimo Carella a,⁎ 

2012

December

ASD-relevant Animal Models of the Foxp Family of Transcription Factors 

J Michael Bowers 1, Genevieve Konopka 1

2012

April

Sequencing chromosomal abnormalities reveals neurodevelopmental loci  that confer risk across diagnostic boundaries 

(Michael E. Talkowski, et al., 2012) 

2012

February

The distinct and overlapping phenotypic spectra of FOXP1 and FOXP2 in  cognitive disorders 

Claire Bacon 1, Gudrun A Rappold 

2011

July

Mild to Moderate Intellectual Disability and Significant Speech and  Language Deficits in Patients with FOXP1 Deletions and Mutations 

Horn D. 

2010

November

Identification of FOXP1 deletions in three unrelated patients with mental  retardation and significant speech and language deficits 

Denise Horn 1, Johannes Kapeller, Núria Rivera-Brugués, Ute Moog, Bettina Lorenz Depiereux, Sebastian Eck, Maja Hempel, Janine Wagenstaller, Alex Gawthrope, Anthony  P Monaco, Michael Bonin, Olaf Riess, Eva Wohlleber, Thomas Illig, Connie R  Bezzina, Andre Franke, Stephanie Spranger, Pablo Villavicencio-Lorini, Wenke  Seifert, Jochen Rosenfeld, Eva Klopocki, Gudrun A Rappold, Tim M Strom 

2010

October

De novo mutations in FOXP1 in cases with intellectual disability, autism,  and language impairment 

Fadi F Hamdan 1, Hussein Daoud, Daniel Rochefort, Amélie Piton, Julie Gauthier, Mathieu  Langlois, Gila Foomani, Sylvia Dobrzeniecka, Marie-Odile Krebs, Ridha Joober, Ronald G  Lafrenière, Jean-Claude Lacaille, Laurent Mottron, Pierre Drapeau, Miriam H  Beauchamp, Michael S Phillips, Eric Fombonne, Guy A Rouleau, Jacques L Michaud 

2010

June

Chiari I malformation, delayed gross motor skills, severe speech delay, and  epileptiform discharges in a child with FOXP1 haploinsufficiency 

Christopher W Carr, Daniel Moreno-De-Luca, Colette Parker, Holly H Zimmerman, Nikki  Ledbetter, Christa Lese Martin, William B Dobyns & Omar A Abdul-Rahman 

2010

March

The forkhead transcription factors, Foxp1 and Foxp2, identify different  subpopulations of projection neurons in the mouse cerebral cortex 

T Hisaoka 1, Y Nakamura, E Senba, Y Morikawa 

2009

September

A 785kb deletion of 3p14.1p13, including the FOXP1 gene, associated with  speech delay, contractures, hypertonia and blepharophimosis 

Mitchel J Pariani 1, Andrew Spencer, John M Graham Jr,