ASD Archives - FOXP1 Foundation

September 2021

Individuals with FOXP1 syndrome present with a complex neurobehavioral profile with high rates of ADHD, anxiety, repetitive behaviors, and sensory symptoms

M. Pilar Trelles, Tess Levy, Bonnie Lerman, Paige Siper, Reymundo Lozano, Danielle Halpern, Hannah Walker, Jessica Zweifach, Yitzchak Frank, Jennifer Foss-Feig, Alexander Kolevzon & Joseph Buxbaum

High rates of ADHD, anxiety, repetitive behaviors, and sensory symptoms in FOXP1 syndrome.

ADHD Anxiety ASD Behavior Clinical Research Treatment

Read summary →

October 2017

Prospective Investigation of FOXP1 Syndrome

Siper ET AL (2017)

A clinical study of nine children (ages 5-12) with FOXP1 syndrome evaluating ASD, language, motor skills and psychiatric features.

ASD Clinical Research Diagnosis Neurodevelopment

Read summary →

October 2015

FoxP1 orchestration of ASD-relevant signaling pathways in the striatum

Daniel J Araujo, Ashley G Anderson, Stefano Berto, Wesley Runnels, Matthew Harper, Simon Ammanuel, Michael A Rieger, Hung-Chung Huang, Kacey Rajkovich, Kristofer W Loerwald, Joseph D Dekker, Haley O Tucker, Joseph D Dougherty, Jay R Gibson, Genevieve Konopka

FOXP1 regulates other genes that are known to be implicated in autism, with mutations increasing activity of striatal neurons.

ASD Gene Expression Neuroscience Striatum

Read summary →