Brain Development Archives - FOXP1 Foundation

March 2020

Single-Cell Analysis of Foxp1-Driven Mechanisms Essential for Striatal Development

Ashley G Anderson, Ashwinikumar Kulkarni, Matthew Harper, Genevieve Konopka

Single-cell analysis reveals how FOXP1 regulates striatal structure and dopamine-receiving cell types.

Brain Development Cell Types Neuroscience Striatum

November 2017

Foxp1 in Forebrain Pyramidal Neurons Controls Gene Expression Required for Spatial Learning and Synaptic Plasticity

Daniel J Araujo, Kazuya Toriumi, Christine O Escamilla, Ashwinikumar Kulkarni, Ashley G Anderson, Matthew Harper, Noriyoshi Usui, Jacob Ellegood, Jason P Lerch, Shari G Birnbaum, Haley O Tucker, Craig M Powell, Genevieve Konopka

Mice with FOXP1 removed from the neocortex and hippocampus showed reduced social interaction, hyperactivity, and spatial learning difficulties.

Brain Development Gene Expression Neuroscience Spatial Learning

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October 2017

Foxp1 regulation of neonatal vocalizations via cortical development

Noriyoshi Usui, Daniel J Araujo, Ashwinikumar Kulkarni, Marissa Co, Jacob Ellegood, Matthew Harper, Kazuya Toriumi, Jason P Lerch, Genevieve Konopka

FOXP1 deletion in the neocortex affects neonatal vocalizations, cortical organisation, and neuron migration in mice.

Brain Development Cortical Development Neuroscience Speech

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