January 2021
Nitin Khandelwal, Sheridan Cavalier, Volodymyr Rybalchenko, Ashwinikumar Kulkarni, Ashley G Anderson, Genevieve Konopka, Jay R Gibson
FOXP1 deletion causes hyperexcitability in striatal D2 neurons through potassium channel regulation.
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March 2020
Ashley G Anderson, Ashwinikumar Kulkarni, Matthew Harper, Genevieve Konopka
Single-cell analysis reveals how FOXP1 regulates striatal structure and dopamine-receiving cell types.
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November 2017
Daniel J Araujo, Kazuya Toriumi, Christine O Escamilla, Ashwinikumar Kulkarni, Ashley G Anderson, Matthew Harper, Noriyoshi Usui, Jacob Ellegood, Jason P Lerch, Shari G Birnbaum, Haley O Tucker, Craig M Powell, Genevieve Konopka
Mice with FOXP1 removed from the neocortex and hippocampus showed reduced social interaction, hyperactivity, and spatial learning difficulties.
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October 2017
Noriyoshi Usui, Daniel J Araujo, Ashwinikumar Kulkarni, Marissa Co, Jacob Ellegood, Matthew Harper, Kazuya Toriumi, Jason P Lerch, Genevieve Konopka
FOXP1 deletion in the neocortex affects neonatal vocalizations, cortical organisation, and neuron migration in mice.
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October 2015
Daniel J Araujo, Ashley G Anderson, Stefano Berto, Wesley Runnels, Matthew Harper, Simon Ammanuel, Michael A Rieger, Hung-Chung Huang, Kacey Rajkovich, Kristofer W Loerwald, Joseph D Dekker, Haley O Tucker, Joseph D Dougherty, Jay R Gibson, Genevieve Konopka
FOXP1 regulates other genes that are known to be implicated in autism, with mutations increasing activity of striatal neurons.
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